It is an autoimmune disease that affects joints.The immune system of our body protect us from the attack of various organisms and foreign bodies but in Rheumatoid arthritis it starts attacking the lining of joints. It is a chronic inflammatory disease which affects the joints. No specific cause known yet but scientific evidence shows the involvement of various factors like-genes, hormones and environmental factors .
American Rheumatism
Association(ARA) Diagnostic Criteria for RA
- RA criteria: (if 5
out of following are present for > 6 weeks);
- morning stiffness;
- pain on motion, or tenderness in at least one joint;
- swelling (soft tissue thickening or fluid, not bony overgrowth alone) in at least one joint;
- swelling of at least one other joint (any interval free of joint symptoms between the two joint);
- poor mucin precipitate from synovial fluid
- characteristic histologic changes in synovium
- swelling (soft tissue thickening or fluid, not bony overgrowth alone) in at least one joint;
- swelling of at least one other joint (any interval free of joint symptoms between the two joint);
- poor mucin precipitate from synovial fluid
- characteristic histologic changes in synovium
- characteristic histologic changes in nodules
- rash of systemic lupus erythematosus
- high concentration of LE cells, or other clear-cut evidence of lupus
- histologic evidence of periarteritis nodosa
- clinical features of dermatomyositis, scleroderma;
- acute rheumatic fever;
- gouty arthritis
- Reiter's syndrome
- shoulder-hand syndrome
- hypertrophic osteoarthropathy
- neuroarthropathy
- alkaptonuria
- multiple myeloma
- erythema nodosum
- leukemia, lymphoma, or agammaglobulinemia
-Joint
–pain,swelling , tenderness ,warmth. Stiffness
in the joint especially early morning.
-Small
joints involvement like wrist, hand,feet
etc. As the disease progresses other
joints like hip ,knee,shoulder and elbows can also get affected.
-Fatigue
and weight loss.
Other organs and body systems affected are:
·
Blood
vessels
·
Mouth
·
Eyes
·
Skin
·
Lungs
·
Salivary
glands
·
Heart
Symptoms of Rheumatoid
arthritis are never constant. They can persists for sometime and then disappear
or reappear after sometime .A flare
(periods of high disease activity) can lasts for few days \months. The symptoms
can come and go.
By: Pooja Dhamija PT